Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.

@article{Kitzman2016EffectOC,
  title={Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.},
  author={Dalane W. Kitzman and Peter R Brubaker and Timothy M. Morgan and Mark Joseph Franklin Haykowsky and Gregory W. Hundley and William E Kraus and Joel D Eggebeen and Barbara J Nicklas},
  journal={JAMA},
  year={2016},
  volume={315 1},
  pages={36-46}
}
IMPORTANCE More than 80% of patients with heart failure with preserved ejection fraction (HFPEF), the most common form of heart failure among older persons, are overweight or obese. Exercise intolerance is the primary symptom of chronic HFPEF and a major determinant of reduced quality of life (QOL). OBJECTIVE To determine whether caloric restriction (diet) or aerobic exercise training (exercise) improves exercise capacity and QOL in obese older patients with HFPEF. DESIGN, SETTING, AND… CONTINUE READING

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