Effect of CGP 20376 on Brugia malayi and parasite antigenemia in jirds.

Abstract

This study was designed to investigate the activity of CGP 20376, a benzothiazole derivative, against Brugia malayi in jirds and to illustrate the utility of parasite antigen detection as a means of monitoring drug efficacy in filariasis. Drug treatment was 100% effective in jirds treated 3 or 24 days after infection. Microfilaria and adult worm counts were… (More)

Topics

Cite this paper

@article{Chandrashekar1991EffectOC, title={Effect of CGP 20376 on Brugia malayi and parasite antigenemia in jirds.}, author={Ramakrishnappa Chandrashekar and D. Subrahmanyam and Gary J Weil}, journal={The Journal of parasitology}, year={1991}, volume={77 3}, pages={479-82} }