Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis.

@article{Kambeitz2012EffectOB,
  title={Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis.},
  author={Joseph P Kambeitz and Sagnik Bhattacharyya and Lana M. Kambeitz-Ilankovic and Isabel Valli and David A. Collier and Philip Mcguire},
  journal={Neuroscience and biobehavioral reviews},
  year={2012},
  volume={36 9},
  pages={2165-77}
}
Brain derived neurotrophic factor (BDNF) is a critical component of the molecular mechanism of memory formation. Variation in the BDNF gene, particularly the rs6265 (val(66)met) single nucleotide polymorphism (SNP), has been linked to variability in human memory performance and to both the structure and physiological response of the hippocampus, which plays a central role in memory processing. However, these effects have not been consistently reported, which may reflect the modest size of the… CONTINUE READING

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