Effect of Aversive Stimulation on 5-Hydroxytryptamine and Dopamine Metabolism in the Rat Brain

@article{Ge1997EffectOA,
  title={Effect of Aversive Stimulation on 5-Hydroxytryptamine and Dopamine Metabolism in the Rat Brain},
  author={Jizhi Ge and Nicholas M. Barnes and Brenda Costall and Robert J. Naylor},
  journal={Pharmacology Biochemistry and Behavior},
  year={1997},
  volume={58},
  pages={775-783}
}
The neurochemical consequences of aversive behavior based on novelty, rat social interaction, have been assessed in various rat brain regions utilizing high-performance liquid chromatography coupled with an electrochemical detector (HPLC-ECD) technique. The present studies indicated that compared to animals from the home cage, those exposed to the high-light aversive unfamiliar test condition, had significantly increased levels of 5-hydroxyindoleacetic acid (5-HIAA), the metabolite of 5… CONTINUE READING

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