Effect of Astroglial Degeneration on Neonatal Blood–Brain Barrier Marker Expression

@article{Krum1996EffectOA,
  title={Effect of Astroglial Degeneration on Neonatal Blood–Brain Barrier Marker Expression},
  author={Janette M Krum},
  journal={Experimental Neurology},
  year={1996},
  volume={142},
  pages={29-35}
}
Numerous studies have demonstrated that astroglial influence is necessary to maintain several blood-brain barrier (BBB) characteristics in CNS-derived endothelial cells in vitro. In the present study, we examined the hypothesis that intact perivascular astrocytes are essential contributors to the maintenance of particular BBB properties within the developing microvasculature of the postnatal rat CNS in situ. Astroglial cells were selectively injured following chronic systemic injections of the… CONTINUE READING

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