Effect of Astaxanthin on Accommodation and Asthenopia-Efficacy-Identification Study in Healthy Volunteers -
@inproceedings{KenjiEffectOA, title={Effect of Astaxanthin on Accommodation and Asthenopia-Efficacy-Identification Study in Healthy Volunteers -}, author={Shiratori Kenji and Ogami Kazuhiro and N. Takuya and Shinmei Yasuhiro and Chin Shinki and Yoshida Kazuhiko and Tsukahara Hiroki and Takehara Isao} }
We evaluated the effect of astaxanthin on visual function in 49 eyes of 49 healthy volunteers. They were over 40 years of age. They were divided into 4 groups matched for age and gender. Each group was given peroral astaxanthin once a day. The dosage was 0mg, 2mg, 4mg, or 12mg for each group. After ingestion of astaxanthin for consecutive 28 days, the uncorrected far visual acuity significantly improved in groups receiving 4mg or 12mg. The accommodation time significantly shortened in groups…
10 Citations
Effect of Astaxanthin on Accommodation and Asthenopia
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It is demonstrated that AX consumption for 4 weeks substantially alleviated symptoms associated with accommodation ability and subjective asthenopia and no safety problems associated with AX consumption were found.
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A Robust Clinical Information on King of Carotenoids: a Systematic Review of the Literature
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Astaxanthin is a red carotenoid pigment extensively found in living organisms and may be effective in treating diseases, including cardiovascular, immune disorders, tumor, diabetes, neurodegenerative conditions and inflammatory conditions.
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The advances of information technology, software and electronics have led to the widespread use of screen based equipment or visual display terminals (VDT) especially at work or leisure and it is likely that current solutions are insufficient to reduce asthenopia.
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A review of approved dose levels, clinical trials of natural AX, and toxicological studies with natural and synthetic AX finds that few safety studies have been conducted in either humans or animals with synthetic AX and recommends the ADI for natural AX to be based only on studies conducted with natural AX.
Scientific opinion on the safety of astaxanthin-rich ingredients (AstaREAL A1010 and AstaREAL L10) as novel food ingredients.
- Chemistry, Medicine
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The Panel concludes that the safety of the NFIs at the proposed use and use levels has not been established and bases the evaluation on the acceptable daily intake (ADI) of 0.034 mg/kg bw for astaxanthin derived by the FEEDAP Panel.
Opinion on the safety of astaxanthin-rich ingredients ( AstaREAL A 1010 and AstaREAL L 10 ) as novel food ingredients 1 EFSA Panel on Dietetic Products , Nutrition and Allergies ( NDA )
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Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the safety of astaxanthin-rich…
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Important and recent developments ranging from cultivation, harvest and postharvest bio-processing technologies to metabolic control and genetic engineering are reviewed in detail, focusing on biomass and astaxanthin production from this biotechnologically important microalga.