Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis

@article{AlexanderCFordMBChB2018EffectOA,
  title={Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis},
  author={MD Frcp Alexander C Ford MBChB and MD Facg Brian E. Lacy PhD and MD Facg Lucinda A. Harris MS and Frcp Facp Macg Frcpi Eamonn MM Quigley MD and PhD Facg Paul Moayyedi MBChB},
  journal={The American Journal of Gastroenterology},
  year={2018},
  pages={1-16}
}
Irritable bowel syndrome (IBS) is a chronic functional bowel disorder that is thought to be due to a disorder of brain–gut function. Drugs acting centrally, such as antidepressants, and psychological therapies may, therefore, be effective. We updated a previous systematic review and meta-analysis of randomized controlled trials (RCTs). MEDLINE, EMBASE, PsychINFO, and the Cochrane Controlled Trials Register were searched (up to July 2017). Trials recruiting adults with IBS, which compared… 

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