Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis

@article{MBChB2018EffectOA,
  title={Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis},
  author={M. F. Alexander C Ford MBChB and M. F. Brian E. Lacy and MS M.LucindaA.Harris and Frcp Facp Macg Frcpi Eamonn MM Quigley and PhD Facg Paul Moayyedi MBChB},
  journal={The American Journal of Gastroenterology},
  year={2018},
  pages={1-16}
}
Irritable bowel syndrome (IBS) is a chronic functional bowel disorder that is thought to be due to a disorder of brain–gut function. Drugs acting centrally, such as antidepressants, and psychological therapies may, therefore, be effective. We updated a previous systematic review and meta-analysis of randomized controlled trials (RCTs). MEDLINE, EMBASE, PsychINFO, and the Cochrane Controlled Trials Register were searched (up to July 2017). Trials recruiting adults with IBS, which compared… Expand

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