Effect of Angiotensin II Type 2 Receptor-Interacting Protein on Adipose Tissue Function via Modulation of Macrophage Polarization

@inproceedings{Jing2013EffectOA,
  title={Effect of Angiotensin II Type 2 Receptor-Interacting Protein on Adipose Tissue Function via Modulation of Macrophage Polarization},
  author={Fei Jing and Masaki Mogi and Li-juan Min and Kousei Ohshima and Hirotomo Nakaoka and Kana Tsukuda and Xiaoli Wang and Jun Iwanami and Masatsugu Horiuchi},
  booktitle={PloS one},
  year={2013}
}
We demonstrated that angiotensin II type 2 (AT2) receptor-interacting protein (ATIP) 1 ameliorates inflammation-mediated vascular remodeling independent of the AT2 receptor, leading us to explore the possibility of whether ATIP1 could exert anti-inflammatory effects and play a role in other pathophysiological conditions. We examined the possible anti-inflammatory effects of ATIP1 in adipose tissue associated with amelioration of insulin resistance. In mice fed a high-cholesterol diet, adipose… CONTINUE READING

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