• Corpus ID: 78650649

Effect of Ananas comosus L. juice on the efficacy of glimepiride in alloxan induced diabetic rats

@inproceedings{Gayasuddin2013EffectOA,
  title={Effect of Ananas comosus L. juice on the efficacy of glimepiride in alloxan induced diabetic rats},
  author={Md. Gayasuddin and Subramanian Kavimani and Sabrina Sait and Gorige Venkataiah and Md. Parvez.},
  year={2013}
}
Food-drug interaction is a challenging concept, since the consumption of food and other herbal drugs is not documented in patient’s profile. With this aspect the present study was designed to investigate the possible effect of Pineapple juice on glimepiride (substrate for CYP2C9) an oral hypoglycemic drug in wistar albino rats. Relative to the standard group (glimepiride 1mg/kg alone treated), the reduction of blood glucose level of test group (Pineapple juice 3mL+glimepiride 1mg/kg treated… 

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