Corpus ID: 51896299

Effect of Amla ( Emblica officinalis ) on Various Physiological and Biochemical Parameters of Metabolic Syndrome

  title={Effect of Amla ( Emblica officinalis ) on Various Physiological and Biochemical Parameters of Metabolic Syndrome},
  author={Manoj Kumar Gupta and Kamlesh Chandra Mathur and Kavita Yadav and Pooja Sharma and Khemlata Tilwani and Pramod Kumar and Narnolia and Bijendra Kumar Binawara},
Amla (Emblica officinalis) has effect on physiological and biochemical parameters of metabolic syndrome due to its anti-inflammatory, hypolipidemic, hypoglycaemic, and anti-oxidative effects. We designed a randomized controlled trial to evaluate the role of Amla therapy in glycaemic control, obesity, hypertension and managing dyslipidemia of metabolic syndrome. The method is One Hundred patients of Metabolic Syndrome were randomized to receive conventional treatment with or without Amla. The… Expand
2 Citations
Evaluation of the effects of a standardized aqueous extract of Phyllanthus emblica fruits on endothelial dysfunction, oxidative stress, systemic inflammation and lipid profile in subjects with metabolic syndrome: a randomised, double blind, placebo controlled clinical study
P. emblica aqueous extract significantly improved endothelial function, oxidative stress, systemic inflammation and lipid profile at both dosages tested, but especially at 500 mg twice daily, which may be used as an adjunct to conventional therapy in the management of metabolic syndrome. Expand
Effect of processing conditions on solvent extraction of Amla (Emblica officinalis) seed oil
The present investigation, “Effect of processing conditions on solvent extraction of Amla (Emblica officinalis) Seed Oil” was undertaken with the objectives to extract oil from Amla seeds atExpand


Amla (Emblica officinalis Gaertn.) prevents dyslipidaemia and oxidative stress in the ageing process
Results indicate that amla may prevent age-related hyperlipidaemia through attenuating oxidative stress in the ageing process by inhibiting NF-κB activation in aged rats. Expand
The protective role of amla (Emblica officinalis Gaertn.) against fructose-induced metabolic syndrome in a rat model
It is suggested that fructose-induced metabolic syndrome is attenuated by the polyphenol-rich fraction of amla. Expand
Effect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients
The results indicated a significant decrease in fasting and 2-h post-prandial blood glucose levels on the 21st day in both normal and diabetic subjects receiving 1, 2 or 3 g E. officinalis powder per day as compared with their baseline values. Expand
Anti-obesity effects of Emblica officinalis (Amla) are associated with inhibition of nuclear transcription factor, peroxisome proliferator-activated receptor gamma (PPAR{gamma})
Emblica officinalis had no significant effect on daily food intake but significantly inhibited body weight gain as well as adipose tissue weights in mice fed HFD, and bioactive-guided fractionation of EO demonstrated that aqueous extract was more effective in inhibiting lipid accumulation. Expand
Antihyperglycaemic and antioxidant effect of hyponidd, an ayurvedic herbomineral formulation in streptozotocin‐induced diabetic rats
The results showed that hyponidd exhibits antihyperglycaemic and antioxidant activity in STZ‐induced diabetic rats. Expand
Effect of the Indian gooseberry (amla) on serum cholesterol levels in men aged 35-55 years.
The effect on total serum cholesterol and its lipoprotein fractions of supplementation of the diet with amla (Emblica officinalis, Gaertn., the Indian gooseberry) was studied in normal andExpand
Insulin sensitizing effect of 3 Indian medicinal plants: An in vitro study
One of the mechanisms for the anti-diabetic effect of Pe, Cl and Tc may be through an insulin sensitizing effect (stimulation of glucose uptake into adipocytes). Expand
Emblica officinalis Exerts Antihypertensive Effect in a Rat Model of DOCA-Salt-Induced Hypertension: Role of (p) eNOS, NO and Oxidative Stress
It is demonstrated that EO reduces oxidative stress, prevents development and progression of hypertension as well as cardiac and renal hypertrophy in DOCA/HS-induced hypertension via modulation of activated eNOS, endogenous antioxidants, serum NO and electrolyte levels. Expand
Antiinflammatory activity of Phyllanthus emblica, Plumbago zeylanica and Cyperus rotundus in acute models of inflammation
Experimental studies conducted earlier have proved that Phyllanthus emblica, Plumbago zeylanica and Cyperus rotundus, plants from the medohara group of Ayurveda possess antiatherosclerotic activity, but whether these drugs exhibit any antiinflammatory activity was of interest. Expand
Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract.
Results indicate that tannoids of E. officinalis are potent inhibitors of AR and suggest that exploring the therapeutic value of natural ingredients that people can incorporate into everyday life may be an effective approach in the management of diabetic complications. Expand