Effect of Adiponectin on Kidney Crystal Formation in Metabolic Syndrome Model Mice via Inhibition of Inflammation and Apoptosis

@inproceedings{Fujii2013EffectOA,
  title={Effect of Adiponectin on Kidney Crystal Formation in Metabolic Syndrome Model Mice via Inhibition of Inflammation and Apoptosis},
  author={Yasuhiro Shimadzu Corpor Fujii and Atsushi Okada and Takahiro Yasui and Kazuhiro Niimi and Yasuhiro Fujii and Masahito Hirose and Yasue Kubota and Keiichi Tozawa and Yutaro Hayashi and Masayuki Usami},
  booktitle={PloS one},
  year={2013}
}
The aims of the present study were to elucidate a possible mechanism of kidney crystal formation by using a metabolic syndrome (MetS) mouse model and to assess the effectiveness of adiponectin treatment for the prevention of kidney crystals. Further, we performed genome-wide expression analyses for investigating novel genetic environmental changes. Wild-type (+/+) mice showed no kidney crystal formation, whereas ob/ob mice showed crystal depositions in their renal tubules. However, this… CONTINUE READING

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