Effect of Acetaminophen on International Normalized Ratio in Patients Receiving Warfarin Therapy

  title={Effect of Acetaminophen on International Normalized Ratio in Patients Receiving Warfarin Therapy},
  author={Gregory J. Hughes and Priti N. Patel and Neera Saxena},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
Warfarin is known to have extensive interactions with many classes of drugs. The literature suggesting a relevant interaction between acetaminophen and warfarin is inconsistent. Considering the ubiquitous use of acetaminophen, a review of the effects on international normalized ratio (INR) in patients taking warfarin was necessary. Thus, we performed a search of the PubMed (1966‐November 2010) and International Pharmaceutical Abstracts (1970‐November 2010) databases to review the available… 

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