Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian Hematologic Substudy.

@article{Merlini2002EffectOA,
  title={Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian Hematologic Substudy.},
  author={Piera Angelica Merlini and Alessandra Repetto and Alessandro Lombardi and Alfredo Vetrano and Raffaela Fetiveau and Claudio Cavallini and Diego Sapp{\`e} and Alessandro Salvioni and Roberto Canziani and Stefano Savonitto and Pier M Mannucci and Diego Ardissino},
  journal={Circulation},
  year={2002},
  volume={105 8},
  pages={928-32}
}
BACKGROUND Abciximab is very effective in reducing major cardiac events in patients undergoing interventional procedures. Its antithrombotic effect is primarily attributable to the blocking of platelet glycoprotein IIb/IIIa receptors, but recent evidence suggests that it may have a direct antithrombin effect. No data are available concerning the effect of… CONTINUE READING