Effect of APE1 T2197G (Asp148Glu) Polymorphism on APE1, XRCC1, PARP1 and OGG1 Expression in Patients with Colorectal Cancer

Abstract

It has been hypothesized that genetic variation in base excision repair (BER) might modify colorectal adenoma risk. Thus, we evaluated the influence of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in normal and tumor samples from patients with colorectal cancer. The results indicate a downregulation of OGG1 and an… (More)
DOI: 10.3390/ijms151017333

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@inproceedings{Santos2014EffectOA, title={Effect of APE1 T2197G (Asp148Glu) Polymorphism on APE1, XRCC1, PARP1 and OGG1 Expression in Patients with Colorectal Cancer}, author={Juliana Carvalho Santos and Alexandre Funck and Isabelle Joyce de Lima Silva-Fernandes and S{\'i}lvia Helena Barem Rabenhorst and C A Mart{\'i}nez and Marcelo Lima Ribeiro}, booktitle={International journal of molecular sciences}, year={2014} }