Effect of AICAR treatment on glycogen metabolism in skeletal muscle.

@article{Aschenbach2002EffectOA,
  title={Effect of AICAR treatment on glycogen metabolism in skeletal muscle.},
  author={William G. Aschenbach and Michael F. Hirshman and Nobuharu Fujii and Kei Sakamoto and Kirsten F. Howlett and Laurie J Goodyear},
  journal={Diabetes},
  year={2002},
  volume={51 3},
  pages={567-73}
}
AMP-activated protein kinase (AMPK) is proposed to stimulate fat and carbohydrate catabolism to maintain cellular energy status. Recent studies demonstrate that pharmacologic activation of AMPK and mutations in the enzyme are associated with elevated muscle glycogen content in vivo. Our purpose was to determine the mechanism for increased muscle glycogen associated with AMPK activity in vivo. AMPK activity and glycogen metabolism were studied in red and white gastrocnemius muscles from rats… CONTINUE READING

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