Effect of 5-hydroxytryptamine on mesenteric hemodynamics in the pig.


The superior mesenteric blood flow response to close intra-arterial infusions of 5-hydroxytryptamine (5-HT) was investigated in anesthetized pigs. Over the entire dose-range studied (0.03-30 mug.animal-1.min-1), 5-HT induced a dose dependent increase in mesenteric blood flow. Following dihydroergotamine, administered intra-arterially, the 5-HT effects were… (More)


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