Effect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2.

@article{Zhang2008EffectO5,
  title={Effect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2.},
  author={Bo Zhang and Chang-liang Wang and Wen-Hua Zhao and Ming Lv and Chun-ying Wang and Wei-xia Zhong and Wu-yuan Zhou and W Yu and Yan Zhang and Sheng Li},
  journal={World journal of gastroenterology},
  year={2008},
  volume={14 16},
  pages={2494-500}
}
AIM To study the effect of 5-lipoxygenase/cyclooxygenase-2 (5-LOX/COX-2) dual inhibitor 7-tert-butyl-2, 3-dihydro-3, 3-dimethyl substituted dihydrofuran 30 (DHDMBF30) on proliferation and apoptosis of the pancreatic cancer cell line Capan-2 and the effect of DHDMBF30 on human pancreatic cancer in a nude mouse model. METHODS Investigate the effect of 5-LOX/COX-2 dual inhibitor DHDMBF30 on proliferation and apoptosis of the pancreatic cancer cell line Capan-2 by RT-PCR, MTT assay, FCM and… CONTINUE READING

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