Effect of 4-methylumbelliferone on the oxidative metabolism of liver mitochondria in jaundiced rats and its relationship of choleretic action.

@article{Yamada1976EffectO4,
  title={Effect of 4-methylumbelliferone on the oxidative metabolism of liver mitochondria in jaundiced rats and its relationship of choleretic action.},
  author={Tomoko Yamada and M Ohshita and Kazue Ozawa and Hidenari Takasan and I. Honjo},
  journal={Arzneimittel-Forschung},
  year={1976},
  volume={26 11},
  pages={2040-2}
}
The effect of 4-methylumbelliferone (4-MU) on the oxidative metabolism of liver mitochondria and its relationship to choleretic action were investigated on 40 bile duct-ligated rats and 40 rats after biliary decompression. The oxidative metabolism of liver mitochondria fell rapidly to 50% of controls within 7 days after bile duct-ligation, whereas that in… CONTINUE READING