Effect of 4-(4'-chlorobenzyloxy)benzyl nicotinate (KCD-232) on cholesterol metabolism in rats.

Abstract

The effects of 4-(4'-chlorobenzyloxy)benzyl nicotinate (KCD-232), a new hypolipidemic agent, on serum cholesterol level and cholesterol biosynthesis were studied in normolipidemic rats. KCD-232 dose-dependently reduced the serum cholesterol level. The in vivo incorporation of [14C]-acetate and 3H from [3H]water into liver digitonin-precipitable sterols was… (More)

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@article{Okada1985EffectO4, title={Effect of 4-(4'-chlorobenzyloxy)benzyl nicotinate (KCD-232) on cholesterol metabolism in rats.}, author={K Okada and Kazumi Yagasaki and Teruhito Mochizuki and Kenzo Takagi and T. Irikura}, journal={Biochemical pharmacology}, year={1985}, volume={34 18}, pages={3361-7} }