Effect of 3-amino benzamide, a poly(adenosine diphosphate-ribose) polymerase inhibitor, in experimental caustic esophageal burn.

@article{Guven2008EffectO3,
  title={Effect of 3-amino benzamide, a poly(adenosine diphosphate-ribose) polymerase inhibitor, in experimental caustic esophageal burn.},
  author={Ahmet Guven and Suzi Demirbağ and Bulent Uysal and Turgut Topal and Esra G{\"u}zel Erdoğan and Ahmet Korkmaz and Haluk Ozturk},
  journal={Journal of pediatric surgery},
  year={2008},
  volume={43 8},
  pages={
          1474-9
        }
}
  • Ahmet Guven, Suzi Demirbağ, +4 authors Haluk Ozturk
  • Published in Journal of pediatric surgery 2008
  • Medicine
  • INTRODUCTION The enzyme poly(adenosine diphosphate-ribose) polymerase affects the repair of DNA in damaged cells. However, its activation in damaged cells can lead to adenosine triphosphate depletion and death. This study was designed to investigate the efficacy of 3-amino benzamide (3-AB), a poly(adenosine diphosphate-ribose) polymerase inhibitor, on the prevention of esophageal damage and stricture-formation development after esophageal caustic injuries in rat. MATERIALS AND METHODS Forty… CONTINUE READING

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