Effect of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in hairy cell leukemia.

@article{Ddi2004EffectO2,
  title={Effect of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in hairy cell leukemia.},
  author={Karel Dědi{\vc} and Pavel Zak},
  journal={Neoplasma},
  year={2004},
  volume={51 1},
  pages={
          56-8
        }
}
The study shows the influence of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in patients with hairy cell leukemia. Eighteen patients were studied; bone marrow fibrosis was graded 0-4 according to the quantity and pattern of distribution of reticulin. The grade of bone marrow fibrosis was established before the therapy and then in 12- and 24-month intervals. Patients showed complete remission after the therapy and remarkable reduction of bone marrow fibrosis. 

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