Effect of 2-Allyl-2-isopropylacetamide on Poly(Adenylic Acid)-Contailing Ribonucleic Acid By MOHINDER K. SARDANA and GOVINDARAJAN

Abstract

A single administration of 2-allyl-2-isopropylacetamide, a porphyrinogenic drug, enhanced the 32P-labelling of nucleoplasmic as well as cytoplasmic poly(A)-containing RNA in rat liver. The synthesis of total microsomal RNA is only marginally increased under these conditions. The drug enhances the labelling of a variety of cytoplasmic poly(A)-containing RNA species, and this effect is counteracted by the simultaneous administration of haemin. 2-Allyl-2-isopropylacetamide also enhanced the release of RNA from the nucleus to the cytoplasm.

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Cite this paper

@inproceedings{Sardana2005EffectO2, title={Effect of 2-Allyl-2-isopropylacetamide on Poly(Adenylic Acid)-Contailing Ribonucleic Acid By MOHINDER K. SARDANA and GOVINDARAJAN}, author={Kabeer Sardana and Govindarajan Padmanaban}, year={2005} }