Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on influenza virus host resistance in mice.

@article{Burleson1996EffectO2,
  title={Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on influenza virus host resistance in mice.},
  author={Gary R Burleson and H Lebrec and Yong George Yang and J D Ibanes and Kevin N Pennington and Linda S Birnbaum},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1996},
  volume={29 1},
  pages={40-7}
}
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes numerous immunotoxic effects including thymic involution and an immunosuppression of nonspecific as well as specific cell- and humoral-mediated immunity. TCDD administration to laboratory animals also results in a decreased resistance to numerous bacteria, viruses, and parasites. Effects on virus host resistance appear to be among the most sensitive effects of TCDD immunotoxicity. However, previous studies have not achieved a no effect level… CONTINUE READING
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