Effect of 17alpha-ethinyl estradiol on active phase rapid eye movement sleep microarchitecture.

@article{Pawlyk2008EffectO1,
  title={Effect of 17alpha-ethinyl estradiol on active phase rapid eye movement sleep microarchitecture.},
  author={Aaron C Pawlyk and Peter D Alfinito and Darlene C. Deecher},
  journal={European journal of pharmacology},
  year={2008},
  volume={591 1-3},
  pages={315-8}
}
Estrogen treatment decreases active phase rapid eye movement (REM) sleep in ovariectomized rats. Here we explored further the effect of 17alpha-ethinyl estradiol (17alpha-EE) on active phase REM sleep in ovariectomized rats by analyzing spectral properties and the number and length of REM sleep bouts. The greatest suppression of REM sleep occurred on day 4 of 17alpha-EE treatment, was due to decreases in bout length, and was accompanied by decreased EEG theta power. These results further… CONTINUE READING

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