Effect of 10-day cast immobilization on sarcoplasmic reticulum calcium regulation in humans.

@article{Thom2001EffectO1,
  title={Effect of 10-day cast immobilization on sarcoplasmic reticulum calcium regulation in humans.},
  author={Jeanette M. Thom and Martin William Thompson and Patricia A. Ruell and Gregory J. Bryant and J S Fonda and Alison Rosemary Harmer and Xanne A K Janse de Jonge and Sandra K Hunter},
  journal={Acta physiologica Scandinavica},
  year={2001},
  volume={172 2},
  pages={141-7}
}
This study investigated the effects of 10-day lower limb cast immobilization on sarcoplasmic reticulum (SR) Ca2+ regulation. Muscle biopsies were analysed in eight healthy females for maximal rates of SR Ca2+ release, Ca2+ uptake and Ca2+ ATPase activity at control, during immobilization at day 3 (IM 3), day 6 (IM 6) and day 10 (IM 10). Quadriceps muscle cross-sectional area (CSA) and 1-repetition maximum (1RM) leg extension strength were measured to determine the extent of muscle size and… CONTINUE READING
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