Effect of 1-p-bromotetramisole on mineralization of hamster tooth germs in vitro: a light and electron microscopic study.


In culture, 10(-3)M 1-p-bromotetramisole (1-pBTM) inhibited mineralization of in vitro secreted enamel matrix in two-day old neonatal hamster first maxillary molar tooth germs. In contrast, in control tooth germs cultured without the inhibitor, new enamel and dentin matrices were secreted and subsequently mineralized in vitro. It is suggested that the… (More)


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