Effect of 1-beta-D-arabinofuranosylcytosine on cell cycle passage time.

@article{Karon1970EffectO1,
  title={Effect of 1-beta-D-arabinofuranosylcytosine on cell cycle passage time.},
  author={M R Karon and Shigeru Shirakawa},
  journal={Journal of the National Cancer Institute},
  year={1970},
  volume={45 5},
  pages={861-7}
}
1-beta-D-Arabinofuranosylcytosine (ara-C) affects the passage rate of cells from S to G2 phase to a greater extent than from G1 to S. This finding is consistent with the fact that the compound may have its major biological effect during the latter part of S and the early part of G2. The magnitude of these effects is related to the dose and duration of ara-C administration. Inhibition of DNA synthesis can occur without disturbances in transit time. 

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