Effect of 1,25-dihydroxycholecalciferol on fracture healing and on general posttraumatic skeletal response in rats.


The authors investigated the effect of 1,25-dihydroxycholecalciferol (1,25(OH)2D3) on the local healing process following an artificial fracture of the rat tibia and on the general posttraumatic response of the skeleton to local trauma. The results showed a significant increase in dry weight of fractured tibias as compared with contralateral intact bones… (More)


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