Effect of (–)-epicatechin-3-gallate and (–)-epigallocatechin-3-gallate on the binding of tegafur to human serum albumin as determined by spectroscopy, isothermal titration calorimetry, and molecular docking

@article{Yuan2019EffectO,
  title={Effect of (–)-epicatechin-3-gallate and (–)-epigallocatechin-3-gallate on the binding of tegafur to human serum albumin as determined by spectroscopy, isothermal titration calorimetry, and molecular docking},
  author={L. Yuan and M. Liu and Yabo Shi and Hui Yan and J. Han and L. Liu},
  journal={Journal of Biomolecular Structure and Dynamics},
  year={2019},
  volume={37},
  pages={2776 - 2788}
}
  • L. Yuan, M. Liu, +3 authors L. Liu
  • Published 2019
  • Chemistry, Medicine
  • Journal of Biomolecular Structure and Dynamics
  • Abstract Green tea has attracted great interest as a cancer prevention agent. Interactions of tea polyphenols with serum albumin may influence the efficacy of drugs. The interactions of (–)-epigallocatechin-3-gallate (EGCG), (–)-epicatechin-3-gallate (ECG), and tegafur (TF) alone or in combination with human serum albumin (HSA) at pH 7.4 and different temperatures were investigated by spectroscopic methods, isothermal titration calorimetry (ITC), and molecular docking. The binding affinities to… CONTINUE READING
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    References

    SHOWING 1-10 OF 46 REFERENCES
    Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study.
    • L. Yuan, M. Liu, +5 authors Min Zhang
    • Chemistry, Medicine
    • Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
    • 2017
    • 28
    Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin.
    • 25
    • Highly Influential
    • PDF
    A major green tea component, (-)-epigallocatechin-3-gallate, ameliorates doxorubicin-mediated cardiotoxicity in cardiomyocytes of neonatal rats.
    • 39