Effect of Δ-9-Tetrahydrocannabinol and Cannabidiol on Nocturnal Sleep and Early-Morning Behavior in Young Adults

  title={Effect of Δ-9-Tetrahydrocannabinol and Cannabidiol on Nocturnal Sleep and Early-Morning Behavior in Young Adults},
  author={A. Nicholson and C. Turner and B. Stone and Philip J Robson},
  journal={Journal of Clinical Psychopharmacology},
  • A. Nicholson, C. Turner, +1 author Philip J Robson
  • Published 2004
  • Psychology, Medicine
  • Journal of Clinical Psychopharmacology
  • Abstract: The effects of cannabis extracts on nocturnal sleep, early-morning performance, memory, and sleepiness were studied in 8 healthy volunteers (4 males, 4 females; 21 to 34 years). The study was double-blind and placebo-controlled with a 4-way crossover design. The 4 treatments were placebo, 15 mg Δ-9-tetrahydrocannabinol (THC), 5 mg THC combined with 5 mg cannabidiol (CBD), and 15 mg THC combined with 15 mg CBD. These were formulated in 50:50 ethanol to propylene glycol and administered… CONTINUE READING
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