Effect-based trigger values for in vitro bioassays: Reading across from existing water quality guideline values.

@article{Escher2015EffectbasedTV,
  title={Effect-based trigger values for in vitro bioassays: Reading across from existing water quality guideline values.},
  author={Beate I Escher and Peta A Neale and Frederic D. L. Leusch},
  journal={Water research},
  year={2015},
  volume={81},
  pages={137-48}
}
Cell-based bioassays are becoming increasingly popular in water quality assessment. The new generations of reporter-gene assays are very sensitive and effects are often detected in very clean water types such as drinking water and recycled water. For monitoring applications it is therefore imperative to derive trigger values that differentiate between acceptable and unacceptable effect levels. In this proof-of-concept paper, we propose a statistical method to read directly across from chemical… CONTINUE READING