Effect(s) of the demineralization process on the osteoinductivity of demineralized bone matrix.

@article{Zhang1997EffectsOT,
  title={Effect(s) of the demineralization process on the osteoinductivity of demineralized bone matrix.},
  author={Ming'ao Zhang and Ralph M. Powers and Lloyd Wolfinbarger},
  journal={Journal of periodontology},
  year={1997},
  volume={68 11},
  pages={1085-92}
}
The relationships between residual calcium levels and particle size of ground demineralized bone matrix and its osteoinductive potential were investigated using in vitro and in vivo assays. The effects of variable residual calcium levels, variable particle sizes, and donor age and gender were studied using a tissue culture-based bioassay (in vitro) as well as an athymic mouse (in vivo) bioassay. The osteoinductive potential of the bone-derived biomaterial was assessed by measuring the degree of… CONTINUE READING

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