Efavirenz: a review.

  title={Efavirenz: a review.},
  author={Saskia M. E. Vrouenraets and Ferdinand W. N. M. Wit and Jacqueline van Tongeren and Joep M. A. Lange},
  journal={Expert opinion on pharmacotherapy},
  volume={8 6},
Efavirenz is a non-nucleoside reverse transcriptase inhibitor that in most treatment guidelines is recommended to be taken combined with two nucleoside analogue reverse transcriptase inhibitors, as a preferred first-line regimen for the treatment of HIV-1 infection. The antiretroviral efficacy of efavirenz-based combination regimens is good, as has been demonstrated in many clinical trials. Efavirenz has a long plasma half-life, which allows for once-daily dosing, but, as a consequence of this… CONTINUE READING

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