Education and APOE-e4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging.

@article{Seeman2005EducationAA,
  title={Education and APOE-e4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging.},
  author={Teresa Seeman and Mei-Hua Huang and Philip M Bretsky and Eileen Crimmins and Lenore L. Launer and Jack Guralnik},
  journal={The journals of gerontology. Series B, Psychological sciences and social sciences},
  year={2005},
  volume={60 2},
  pages={P74-83}
}
Longitudinal data from the MacArthur Study of Successful Aging were used to test for interactions between education and apolipoprotein E (APOE) genotype with respect to time trends in cognitive performance. Interactions between education, APOE-e4 status, and time were found for overall cognitive function, and for subscales measuring memory and naming: The presence of the e4 allele was associated with steeper declines in cognition for those with a greater than eighth-grade education. For those… CONTINUE READING

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