Education, cognitive function, and severity of neuropathology in Alzheimer disease

  title={Education, cognitive function, and severity of neuropathology in Alzheimer disease},
  author={Thomas D. Koepsell and Brenda F. Kurland and Ofer Harel and Elise A Johnson and X. H. Zhou and Walter A Kukull},
  pages={1732 - 1739}
Background: Education may modulate the degree to which the neuropathology of Alzheimer disease (AD) is expressed as impaired cognitive performance. Methods: We studied 2,051 participants age 65+ years at 27 AD Centers who died and underwent autopsy. All took the Mini-Mental State Examination (MMSE) within 2 years before death. Braak & Braak stage, neuritic plaque density, and Consortium to Establish a Registry for Alzheimer’s Disease and National Institute on Aging (NIA)/Reagan diagnostic… 

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