Eczema and ceramides: an update

@article{Jungersted2013EczemaAC,
  title={Eczema and ceramides: an update},
  author={J. M. Jungersted and T. Agner},
  journal={Contact Dermatitis},
  year={2013},
  volume={69}
}
Although normal epidermal barrier function depends on numerous factors, including corneocytes, lipids, enzymes, pH, and calcium gradient, the key players are lipids and proteins in the stratum corneum. Atopic dermatitis is characterized by barrier abnormalities, such as the presence of filaggrin mutations in almost 50% of patients with moderate/severe atopic dermatitis, and lipid disturbances, mainly expressed as insufficient ceramides. In this review, with an emphasis on human studies, we… Expand
Evaluation of a Pseudoceramide Moisturizer in Patients with Mild-to-Moderate Atopic Dermatitis
Local rhamnosoft, ceramides and L-isoleucine in atopic eczema: a randomized, placebo controlled trial.
  • A. Marseglia, A. Licari, +5 authors G. Marseglia
  • Medicine
  • Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
  • 2014

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