Ectopically expressed IBP promotes cell proliferation in oral squamous cell carcinoma.

@article{Jian2012EctopicallyEI,
  title={Ectopically expressed IBP promotes cell proliferation in oral squamous cell carcinoma.},
  author={Cong-xiang Jian and Ming-zhen Yang and Peng Li and Jian Xiong and Zhu-jun Zhang and Chen-Jun Li and An Qing Chen and Chuan-min Hu and Ji-xiang Zhou and Shu-hui Li},
  journal={Cancer investigation},
  year={2012},
  volume={30 10},
  pages={748-56}
}
IFN regulatory factor 4 binding protein (IBP) has been shown to play an important role in the progression of malignant tumors such as breast cancer cells, but its function in oral squamous cell carcinoma (OSCC) remains unclear. We found that IBP ectopically expressed in some OSCC specimens but not in normal oral mucosa epithelium tissues. IBP expression was significantly correlated with tumor size, differentiation, clinical stage, and distant metastasis. Furthermore, IBP markedly promoted OSCC… CONTINUE READING