• Biology, Medicine
  • Published in Journal of cell science 1998

Ectopic skeletal muscles derived from myoblasts implanted under the skin.

@article{Irintchev1998EctopicSM,
  title={Ectopic skeletal muscles derived from myoblasts implanted under the skin.},
  author={A. Irintchev and Joseph D. Rosenblatt and Michael John Cullen and Margit Zweyer and Anton Wernig},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 22)},
  pages={
          3287-97
        }
}
We investigated the potential of cultured myoblasts to generate skeletal muscle in an ectopic site. Myoblasts from a clonal cell line or from expanded primary cultures were injected under the skin of the lumbar region of adult syngenic Balb/c mice. One to 7 weeks after injection, distinct muscles, of greater mass in mice injected with clonal myoblasts (6-78 mg, n=37) than in mice injected with primary myoblasts (1-7 mg, n=26), had formed between the subcutaneous panniculus carnosus muscle and… CONTINUE READING

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