Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue

THE Brachyury (T) gene is required cell-autonomously for mesoderm formation in the posterior of the mouse embryo1,2, and both its complementary DNA sequence and expression pattern3 closely resemble those of a Xenopus homologue (Xbra)4, suggesting that these genes have an evolutionarily conserved function in vertebrate development. Strong expression of Xbra… (More)