Ectopic integration of transforming DNA is rare among neurospora transformants selected for gene replacement.

Abstract

In a variety of organisms, DNA-mediated transformation experiments commonly produce transformants with multiple copies of the transforming DNA, including both selected and unselected molecules. Such "cotransformants" are much more common than expected from the individual transformation frequencies, suggesting that subpopulations of cells, or nuclei, are… (More)

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@article{Miao1995EctopicIO, title={Ectopic integration of transforming DNA is rare among neurospora transformants selected for gene replacement.}, author={Vivian P. W. Miao and Michael R. Rountree and E. U. Selker}, journal={Genetics}, year={1995}, volume={139 4}, pages={1533-44} }