Ectopic growth hormone-releasing hormone secretion by thymic carcinoid tumour.

@article{Boix2002EctopicGH,
  title={Ectopic growth hormone-releasing hormone secretion by thymic carcinoid tumour.},
  author={Evangelina Boix and Antonio Pic{\'o} and R J Carlos Pinedo and Izaurieta Aranda and K{\'a}lm{\'a}n Kov{\'a}cs},
  journal={Clinical endocrinology},
  year={2002},
  volume={57 1},
  pages={
          131-4
        }
}
The case of a 33-year-old-woman with Multiple Endocrine Neoplasia Type 1 (MEN1) syndrome and acromegaly due to ectopic growth hormone-releasing hormone (GHRH) secretion by a thymic carcinoid tumour is reported. Immunohistochemistry revealed positive immunoreactivity for GHRH, vasoactive intestinal polypeptide, somatostatin and alpha-subunit in the tumour cells. A previously undescribed new germ line mutation of the MEN1 protein gene was revealed. 
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