Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice.

@article{He2005EctopicGE,
  title={Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice.},
  author={Bai-Cheng He and Scott Counts and Sylvia E. Perez and John G. Hohmann and James Benjamin Koprich and Jack W Lipton and Robert A Steiner and Jacqueline N. Crawley and Elliott J. Mufson},
  journal={Neuroscience},
  year={2005},
  volume={133 2},
  pages={371-80}
}
The functional interactions of the neuropeptide galanin (GAL) occur through its binding to three G protein-coupled receptor subtypes: galanin receptor (GALR) 1, GALR2 and GALR3. Previously, we demonstrated that GALR1 mRNA expression was increased in the CA1 region of the hippocampus and discrete hypothalamic nuclei in galanin transgenic (GAL-tg) mice. This observation suggested a compensatory adjustment in cognate receptors in the face of chronic GAL exposure. To evaluate the molecular… CONTINUE READING