Ectopic bioactive luteinizing hormone secretion by a pancreatic endocrine tumor, manifested as luteinized granulosa-thecal cell tumor of the ovaries.

@article{Piaditis2005EctopicBL,
  title={Ectopic bioactive luteinizing hormone secretion by a pancreatic endocrine tumor, manifested as luteinized granulosa-thecal cell tumor of the ovaries.},
  author={Georgios P Piaditis and A Angellou and George Kontogeorgos and Nikos Mazarakis and Theodora Kounadi and Gregory A. Kaltsas and Kyriakos Vamvakidis and Ricardo Vincent Lloyd and Eva Horv{\'a}th and K{\'a}lm{\'a}n Kov{\'a}cs},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 4},
  pages={2097-103}
}
Endocrine pancreatic tumors are rare neoplasms consisting of multipotent cells capable of secreting various bioactive substances causing characteristic clinical syndromes. Ovarian stromal hyperthecosis is characterized by varying degrees of luteinized stromal cell proliferation after sustained LH and/or human chorionic gonadotropin stimulation, clinically manifested by symptoms/signs of virilization resembling the polycystic ovary syndrome (PCOS). We report a case of ectopic bioactive LH… CONTINUE READING