Economic evaluations in bipolar disorder: a systematic review and critical appraisal

@article{Pari2014EconomicEI,
  title={Economic evaluations in bipolar disorder: a systematic review and critical appraisal},
  author={Anees Ahmed Abdul Pari and J. Simon and J. Wolstenholme and J. Geddes and G. Goodwin},
  journal={Bipolar Disorders},
  year={2014},
  volume={16},
  pages={557 - 582}
}
Bipolar disorder (BD) is a chronic illness and is one of the worldwide leading causes of disability. It is often a lifelong illness and incurs a substantial economic burden on the health care system, the patients, and society as a whole. However, there are few studies evaluating the economic impact of alternative strategies in the management of BD. 
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References

SHOWING 1-10 OF 68 REFERENCES
Economic evidence in affective disorders: a review
  • M. Löthgren
  • Political Science, Medicine
  • The European Journal of Health Economics
  • 2005
There is a fairly poor evidence base available on cost of substance abuse in Europe, where the most recent studies are performed in the middle of the 1990s, and cover only the major EuropeanExpand
Cost Effectiveness of Quetiapine in Patients with Acute Bipolar Depression and in Maintenance Treatment after an Acute Depressive Episode
TLDR
Compared with olanzapine, the results suggest that quetiapine is cost effective as a maintenance treatment for bipolar depression. Expand
Cost-effectiveness of clinical interventions for reducing the global burden of bipolar disorder
TLDR
Community-based interventions for bipolar disorder were estimated to be more efficient than hospital-based services, each DALY averted costing between one and three times average gross national income. Expand
A model of the economic impact of a bipolar disorder screening program in primary care.
TLDR
A 1-time screening program for bipolar disorder, when patients first present with a major depressive episode, can reduce health care costs to managed-care plans. Expand
Annual cost of managing bipolar disorder to the UK healthcare system.
TLDR
The direct medical cost of managing bipolar disorder in the UK healthcare system is considerable and therapeutic strategies that optimize community-based management, prevention of recurrence and hospitalization could reduce the economic burden of this illness. Expand
Long-Term Prophylaxis in Bipolar Disorder
TLDR
The available evidence for a range of pharmacological options is summarized, guidance on common issues in clinical management in line with current practice guidelines is provided, and gradual tapering of dose over weeks or months is recommended. Expand
Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder
TLDR
Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder are made. Expand
Pharmacoeconomics of quetiapine for the management of acute mania in bipolar I disorder
TLDR
A comparison of the total costs demonstrates that all of the monotherapy options and placebo are more costly than the combination treatment options, and the combination of lithium/quetiapine and olanzapine/lithium was superior in terms of serious side effects. Expand
Depressive and manic symptoms are not opposite poles in bipolar disorder
TLDR
Depressive and manic symptoms are not opposite poles in bipolar disorder. Expand
Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial.
TLDR
Divalproex maintenance treatment for bipolar disorder resulted in comparable medical costs, clinical and QOL outcomes compared with lithium. Expand
...
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3
4
5
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