Economic evaluation of major knee surgery with recombinant activated factor VII in hemophilia patients with high titer inhibitors and advanced knee arthropathy: exploratory results via literature-based modeling

@article{Ballal2008EconomicEO,
  title={Economic evaluation of major knee surgery with recombinant activated factor VII in hemophilia patients with high titer inhibitors and advanced knee arthropathy: exploratory results via literature-based modeling},
  author={R. Ballal and M. Botteman and I. Foley and J. Stephens and C. Wilke and A. V. Joshi},
  journal={Current Medical Research and Opinion},
  year={2008},
  volume={24},
  pages={753 - 768}
}
  • R. Ballal, M. Botteman, +3 authors A. V. Joshi
  • Published 2008
  • Medicine
  • Current Medical Research and Opinion
  • ABSTRACT Objectives: People with severe hemophilia suffer from frequent intra-articular hemorrhages, leading to pain, swelling, reduced flexion, and arthropathy. Elective orthopedic surgery using factor VIII (FVIII) replacement to prevent uncontrolled bleeding has been endorsed as an effective treatment option for patients with severe or advanced hemophilic arthropathy. These surgeries reduce pain, restore mobility and function, and reduce the frequency of recurrent joint bleeds. Unfortunately… CONTINUE READING
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