Economic and quality of life outcomes of antiretroviral therapy for HIV/AIDS in developing countries: a systematic literature review

@article{Beard2009EconomicAQ,
  title={Economic and quality of life outcomes of antiretroviral therapy for HIV/AIDS in developing countries: a systematic literature review},
  author={Jennifer Beard and Frank G. Feeley and Sydney Rosen},
  journal={AIDS Care},
  year={2009},
  volume={21},
  pages={1343 - 1356}
}
Abstract The impacts of antiretroviral therapy (ART) on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be measured. We conducted a systematic literature review to analyze the effect of ART on these economic and quality of life indicators in developing countries and assess the state of research on these topics. We searched Ovid/Medline, PubMed, Psych Info, Web of Science, Google Scholar, and… 
Economic Outcomes of Patients Receiving Antiretroviral Therapy for HIV/AIDS in South Africa Are Sustained through Three Years on Treatment
TLDR
Some of the positive economic and social externalities anticipated as a result of large-scale treatment provision, such as increases in workforce participation and productivity and the ability of patients to carry on normal lives, may indeed be accruing.
The Impact of ART on the Economic Outcomes of People Living with HIV/AIDS
TLDR
ART was associated with greater improvement in work status, even after controlling for change in physical health functioning, suggesting other factors associated with ART may influence work.
Quality of Life Outcomes of Antiretroviral Treatment for HIV/AIDS Patients in Vietnam
  • B. Tran
  • Medicine, Psychology
    PloS one
  • 2012
TLDR
Strengthening the quality of ART services at the provincial and district levels, gender-specific impact mitigation, and early treatment supports are recommended for further expansion ofART services in Vietnam.
Does duration on antiretroviral therapy determine health-related quality of life in people living with HIV? A cross-sectional study in a regional referral hospital in Kenya
TLDR
Patients on ART for a relatively longer duration reported poorer HRQoL at the study facility independent of the effect of other therapy-related, clinical, and sociodemographic factors, which may have negative repercussions on the substantial gains made against the HIV scourge.
AIDS treatment and mental health: evidence from Uganda.
Quality of life of people living with HIV and AIDS in Swaziland who are on antiretroviral therapy
TLDR
The study concluded that PLWHA in Swaziland who are on antiretroviral therapy (ART) are powerless to deal with the above challenges and improve their QOL.
Effect of antiretroviral therapy on patients’ economic well being: five-year follow-up
TLDR
Results from one of the longest prospective cohorts tracking economic outcomes of HIV treatment in Africa suggest continuous improvement during the first 5 years on treatment, confirming the sustained economic benefits of providing large-scale treatment.
Improved quality of life with immediate versus deferred initiation of antiretroviral therapy in early asymptomatic HIV infection
TLDR
There were modest but significant improvements in self-assessed QOL among those initiating ART immediately compared to deferring treatment, supporting patient-perceived health benefits of initiating ART as soon as possible after an HIV diagnosis.
Prospective cohort study of the impact of antiretroviral therapy on employment outcomes among HIV clients in Uganda.
TLDR
Improvements in general health, reduction in the incidence of pain and health interfering with work, as well as improvements in work-related self-efficacy for both groups over time, but significantly more so for the group receiving ART treatment.
Determinants of health-related quality of life in adults living with HIV in Vietnam
TLDR
The findings highlight the need to improve the health service referral system and enhance psychological and social supports for patients in early stages of HIV infection in Vietnam.
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