Economic Evaluations of Childhood Influenza Vaccination

  title={Economic Evaluations of Childhood Influenza Vaccination},
  author={Anthony T. Newall and Mark Jit and Ph Beutels},
The potential benefits of influenza vaccination programmes targeted at children have gained increasing attention in recent years.We conducted a literature search of economic evaluations of influenza vaccination in those aged ≤18 years. The search revealed 20 relevant articles, which were reviewed. The studies differed widely in terms of the costs and benefits that were included. The conclusions were generally favourable for vaccination, but often applied a wider perspective (i.e. including… 

Understanding the Cost-Effectiveness of Influenza Vaccination in Children: Methodological Choices and Seasonal Variability

Universal childhood influenza vaccination is likely to be cost-effective if a substantial herd protection effect can be achieved by the program, however, it is important that decision makers understand the role of seasonal variability and the impact of alternative methodological choices in economic evaluations of influenza vaccination.

Cost-effectiveness of childhood influenza vaccination in Europe: results from a systematic review

The literature review showed that all studies identified highlight that paediatric vaccinations using a live vaccine, especially in the quadrivalent formulation, are cost-effective compared to current vaccinations (elderly and at-risk groups with TIV or no vaccination).

Key issues for estimating the impact and cost-effectiveness of seasonal influenza vaccination strategies

Given the importance of knowing the impact of changes to influenza policy, such complexities need careful treatment using tools such as population-based trial designs, meta-analyses, time-series analyses and transmission dynamic models.

Economic Evaluation of Vaccination Programmes in Older Adults and the Elderly: Important Issues and Challenges

It is argued that it is important to more fully consider some important issues and challenges of vaccination programmes targeted at older adults and the elderly in high-income countries.

Inclusion of Safety-Related Issues in Economic Evaluations for Seasonal Influenza Vaccines: A Systematic Review

Although the overall impact of AEFIs on the cost-effectiveness outcomes was found to be low, it is urged that their inclusion in economic evaluations of seasonal influenza vaccines to reflect comprehensive reports for the decision makers and end-users of the vaccination strategies is urged.

Systematic Review of the Cost-Effectiveness of Influenza Immunization Programs: A Canadian Perspective

Overall, universal mass immunization programs were favoured as a cost-effective strategy and quadrivalent vaccines and the inclusion of new technologies and programmatic strategies would provide more insight regarding immunization policy decisions.

The social and economic impact of community-based transmission of vaccine-preventable influenza and measles

The findings demonstrate the need for adherence to preventative vaccination programmes to reduce the potential for outbreaks of influenza and measles and demonstrate the importance of adherence to school-based vaccination policies.

Economic benefits of inactivated influenza vaccines in the prevention of seasonal influenza in children

It can be concluded, that inactivated influenza vaccination of children is a very efficient intervention.

Childhood and adolescent influenza vaccination in Europe: A review of current policies and recommendations for the future

Key policy considerations for European countries that must be considered when extending vaccination programmes to younger age groups are discussed alongside recommendations for European policy makers based on the findings.



Economic evidence of influenza vaccination in children.

Cost Effectiveness of Influenza Vaccination in Older Adults

The estimates of serious outcomes due to influenza and the estimates of vaccine effectiveness against these outcomes were found to have the most influence on cost effectiveness.

Economic Impact of Influenza Vaccination in Preschool Children

Vaccinating preschool children with inactivated influenza vaccine is economically advantageous and serious consideration should be given to recommending vaccination in this age group.

Clinical and economic impact of influenza vaccination on healthy children aged 2-5 years.

Cost-effectiveness of influenza vaccination in high-risk children in Argentina.

Cost-effectiveness of influenza vaccination of healthy children.

Benefits and costs of immunizing children against influenza at school: an economic analysis based on a large-cluster controlled clinical trial.

Examination of the cost consequences of a large multistate, school-based influenza immunization program shows that immunization reduces disease among children and adults and is cost-saving to society.

Potential Cost Savings Attributable to Influenza Vaccination of School-aged Children

Vaccination of school-aged children against influenza could have substantial financial benefits to society, especially if performed in a group-based setting.

Influenza Vaccination: Cost-effectiveness and Public Policy

The analysis indicates the need for epidemiologic research on the extent of influenza and the mechanism of its spread and raises the issue of public policy to promote influenza vaccination among high-risk persons as a low-cost, preventive technology.