Economic Benefits of Treating High-Risk Hypertension with Angiotensin II Receptor Antagonists (Blockers)

@article{Coca2008EconomicBO,
  title={Economic Benefits of Treating High-Risk Hypertension with Angiotensin II Receptor Antagonists (Blockers)},
  author={Antonio Coca},
  journal={Clinical Drug Investigation},
  year={2008},
  volume={28},
  pages={211-220}
}
  • A. Coca
  • Published 2008
  • Medicine
  • Clinical Drug Investigation
Hypertension is one of the leading risk factors for cardiovascular disease and represents a major health and economic burden. Most patients with high-or very high-risk hypertension have multiple cardiovascular risk factors with or without accompanying subclinical organ damage or established cardiovascular or renal disease. Patients with severe hypertension or with moderate hypertension and one to two additional risk factors have absolute 10-year risks of cardiovascular disease of 21–30% and 15… 
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14 Citations
Background Citations
4
Methods Citations
1

14 Citations

Costs of current antihypertensive therapy in Switzerland: an economic evaluation of 3,489 patients in primary care.

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The prescription of mono-therapies appears to be a major cost factor, thus, the use of single-pill-combination therapy can be considered as a suitable approach to saving costs throughout all BP- stages.

Comparison of the efficacy and safety of an oral combination of losartan, hydrochlorothiazide and simvastatin against separated components, in hypertensive and dyslipidemic patients

TLDR
It is concluded that the fixed dose combination of losartan, hydrochlorothiazide and simvastatin, is as effective and safe as the fixed doses ofLosartan and hydrochlorothsiazide plus simvastsatin, in hypertensive and hypercholesterolemic patients.

Hypertension treatment in a section of the prescribed management benefit market in South Africa

TLDR
This research was embedded in a drug utilisation review approach supported by various other measuring instruments, classification systems, arithmetical formulas and descriptive statistical methods and revealed that most observations were made for prescriptions consisting of two and three-item antihypertensive medications respectively.

Evolutionary cost analysis of valsartan initiation among patients with hypertension: a time series approach

TLDR
The evolutionary impact of the initiation of valsartan included a temporary cost surge, a gradual, consistent, and statistically significant cost decrease, and a cost-offset point around the 4th post-initiation month.

Upregulation of Renin Angiotensin Aldosterone System (RAAS) by Methylglyoxal: Role in Hypertension

TLDR
This review focuses on the literature review of hypertension and its role in diabetes, as well as some of the mechanisms behind its prevalence and treatment.

ORAL BIO-EQUIVALENCE STUDY OF FIXED DOSE COMBINATION OF OLMESARTAN 40mg+AMLODIPINE 10mg+ HYDROCHLOROTHIAZIDE 25mg TABLETS IN HEALTHY HUMAN VOLUNTEERS

TLDR
The primary pharmacokinetic parameters (C max, A UC 0-t and AUC 0-inf ) 90%CI were within the 80 to 125% interval required for bioequivalence as stipulated in the current regulations of the USFD A acceptance criteria.

Original article Evolutionary cost analysis of valsartan initiation among patients with hypertension: a time series approach

TLDR
This study examines the evolutionary impact of valsartan initiation on medical costs through a retrospective time series study design with a large, US national commercial claims database for the period of 2004–2008.

A Retrospective Survey of the Incidence of Hypertension in Abia State-Nigeria

TLDR
The incidence of Hypertension increases as the year goes by, hence the need for life style modification, and it was observed that the incidence was higher in men than in women.

Role of Neuronal Nitric Oxide Synthase on Cardiovascular Functions in Physiological and Pathophysiological States.

Decision and Simulation Modeling in Systematic Reviews

TLDR
The modeling analyses were classified according to the type of interventions that were evaluated: prevention, screening, diagnosis, and treatment.

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