Ecology of the aging human brain.

@article{Sonnen2011EcologyOT,
  title={Ecology of the aging human brain.},
  author={Joshua A. Sonnen and Karen Santa Cruz and Laura Sue Hemmy and Randall L. Woltjer and James Ba Leverenz and Kathleen S. Montine and Clifford R. Jack and Jeffrey Kaye and Kelvin Lim and Eric B. Larson and Lon White and Thomas J. Montine},
  journal={Archives of neurology},
  year={2011},
  volume={68 8},
  pages={
          1049-56
        }
}
BACKGROUND Alzheimer disease, cerebral vascular brain injury, and isocortical Lewy body disease (LBD) are the major contributors to dementia in community- and population-based studies. OBJECTIVE To estimate the prevalence of clinically silent forms of these diseases in cognitively normal (CN) adults. DESIGN Autopsy study. SETTING Community- and population based. PARTICIPANTS A total of 1672 brain autopsies from the Adult Changes in Thought study, Honolulu-Asia Aging Study, Nun Study… CONTINUE READING
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