Eckol protects V79-4 lung fibroblast cells against gamma-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH(2)-terminal kinase pathway.

@article{Zhang2008EckolPV,
  title={Eckol protects V79-4 lung fibroblast cells against gamma-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH(2)-terminal kinase pathway.},
  author={Rui Zhang and Kyoung Ah Kang and Mei Jing Piao and Dong Ok Ko and Zhi Hong Wang and In Kyung Lee and Bum Joon Kim and Il Yun Jeong and Taekyun Shin and Jae Woo Park and N. H. Lee and Jin Won Hyun},
  journal={European journal of pharmacology},
  year={2008},
  volume={591 1-3},
  pages={114-23}
}
The radioprotective effect of eckol against gamma-ray radiation-induced oxidative stress and its possible protective mechanisms were investigated. Eckol was found to reduce the intracellular reactive oxygen species generated by gamma-ray radiation. Moreover, eckol also protected against radiation-induced cellular DNA damage and membrane lipid peroxidation, which are the main targets of radiation-induced damage. In addition, eckol recovered the cell viability damaged by radiation via the… CONTINUE READING

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